The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
A1S9T and BN75 temperature sensitivity complementing; A1S9T and BN75 temperature sensitivity complementing POC20 centriolar protein homolog UBA1 ubiquitin-activating enzyme E1 homolog A ubiquitin-like modifier-activating enzyme 1; POC20 centriolar protein homolog; Protein A1S9; testicular secretory protein Li 63; uba1 {ECO:0000312|EMBL:AAH85791.1, ECO:0000312|RGD:1359327}; UBA1, ubiquitin-activating enzyme E1 homolog A; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 X; ubiquitin-activating enzyme E1 {ECO:0000250|UniProtKB:Q02053}; ubiquitin-activating enzyme E1, Chr X; ubiquitin-like modifier activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1 X; ubiquitin-like modifier-activating enzyme 1 {ECO:0000250|UniProtKB:Q02053}
Cat # 11556081
100 µL
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